Diastolic function in hypertrophic cardiomyopathy

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منابع مشابه

Hypertrophic cardiomyopathy and diastolic dysfunction.

Hypertrophic cardiomyopathy (HCM) is a disease state with characteristic pathologic changes most likely to result in abnormalities of diastolic function. Indeed, HCM may well be considered a “poster child” for diastolic dysfunction, because pronounced ventricular hypertrophy is associated with a reduced left ventricular (LV) cavity. The pressurevolume relationship would almost certainly be shif...

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Left ventricular diastolic gradient in hypertrophic cardiomyopathy☆

Systolic left ventricular (LV) gradients and diastolic dysfunction are widely studied in hypertrophic cardiomyopathy (HCM) [1,2], however diastolic gradients have never been described. A patient with HCM, mid-cavity obliteration and apical aneurysm, diagnosed by both 2D echocardiography (Fig. 1, panel A) and cardiac magnetic resonance (Fig. 1, panel B), showed color Doppler aliasing effect at m...

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Autonomic function in hypertrophic cardiomyopathy.

BACKGROUND Autonomic dysfunction has been found to be a powerful predictor of arrhythmic events and sudden death after myocardial infarction. Hypertrophic cardiomyopathy carries a risk of sudden death and this risk is increased by the occurrence of syncope. OBJECTIVES To determine if autonomic dysfunction occurs in patients with hypertrophic cardiomyopathy and if it is associated with the occ...

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Diastolic dysfunction in familial hypertrophic cardiomyopathy transgenic model mice.

AIMS Several mutations in the ventricular myosin regulatory light chain (RLC) were identified to cause familial hypertrophic cardiomyopathy (FHC). Based on our previous cellular findings showing delayed calcium transients in electrically stimulated intact papillary muscle fibres from transgenic Tg-R58Q and Tg-N47K mice and, in addition, prolonged force transients in Tg-R58Q fibres, we hypothesi...

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Diastolic gradient in hypertrophic cardiomyopathy of the apical type.

Diastolic intracavitary gradient in the left ventricle is a common finding in patients with apical hypertrophy. We report the case of a patient with hypertrophic cardiomyopathy and midventricular obstruction. The paradoxical jet flow in this patient, during diastole, was directed towards the base away from the apex.

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 1992

ISSN: 0735-1097

DOI: 10.1016/0735-1097(92)90395-4